Andrew Radin, MBA
CEO & Co-Founder
Biotech entrepreneur with experience building drug-development companies and executing biopharma partnerships.
Targeted biologics for pain
Numb Corp
Engineering a non-opioid, long-lasting, regional approach to pain control.
Numb Corp is developing targeted biologics designed to selectively modulate sensory neurons and provide durable local pain control without systemic opioid exposure.
Our Approach
Targeted biologics for regional pain control.
Numb Corp is developing TRPV1-targeted, botulinum-derived biologics designed to selectively enter sensory neurons and produce prolonged local inhibition of neurotransmission.
Our goal is to create locally administered therapeutics that provide durable regional pain control while avoiding the systemic exposure associated with conventional pain medicines.
A regional problem may not require a systemic solution.
Why It Matters
Regional pain is often treated with systemic therapies.
Even when the underlying pain signal is anatomically localized, patients are often treated with medicines that act throughout the body.
Numb Corp is developing a targeted approach intended to control pain closer to its source, with the potential for durable effects from a locally administered biologic.
Leadership
Lief Fenno, MD, PhD
CSO & Co-Founder
Molecular bioengineer, neuroscientist, and physician focused on translational neuroscience and protein engineering.
Tim Machado, PhD
Co-Founder & Scientific Advisor
Neuroscientist and technology entrepreneur; co-founder of CTRL-Labs.
Affiliations & Scientific Presence
Connected to leading innovation and neuroscience communities.
MIT STEX
Numb Corp has participated in the MIT STEX ecosystem.
StartX Med
Numb Corp has participated in the StartX Med community.
Society for Neuroscience
Numb Corp has presented scientific work at the Society for Neuroscience Annual Meeting.
Strategic Partnerships
Advancing the platform with the right partners.
Numb Corp is exploring strategic partnerships to advance its platform and therapeutic programs.
contactus@numbcorp.com